Justin Gaethje will face fellow American Max Holloway for the symbolic BMF title at UFC 300 on 13 April.
The lightweight contest is the latest fight to be added to the UFC’s landmark event in Las Vegas.
Gaethje, 35, won the BMF title last July when he knocked out Dustin Poirier while it is 32-year-old Holloway’s first fight at lightweight since 2019.
Jim Miller, who fought at UFC 100 and UFC 200, will also feature at UFC 300 against Bobby Green.
Veteran lightweight Miller turns 41 in August and is the all-time leader for wins in the UFC with 26.
The BMF title is awarded to the ‘baddest’ fighter in the UFC and has only been contested twice since its inauguration in 2019.
Former featherweight champion Holloway last fought at lightweight four years ago when he lost to Poirier for the interim title.